![]() ![]() Quantify symmetry of imprecision with Hougaard’s skewness.Confidence intervals can be symmetrical (as is traditional) or asymmetrical (which is more accurate). Quantify precision of fits with SE or CI of parameters.Automatically graph curve over specified range of X values.Accept automatic initial estimated values or enter your own.Differentially weight points by several methods and assess how well your weighting method worked.Compare models using extra sum-of-squares F test or AICc.Automatic outlier identification or elimination.Global nonlinear regression – share parameters between data sets.Enter different equations for different data sets.Enter differential or implicit equations.Now including family of growth equations: exponential growth, exponential plateau, Gompertz, logistic, and beta (growth and then decay). Fit one of our 105 built-in equations, or enter your own.Comparison of data from nested data tables using nested t test or nested one-way ANOVA (using mixed effects model).Analysis of repeated measures data (one-, two-, and three-way) using a mixed effects model (similar to repeated measures ANOVA, but capable of handling missing data).Three-way ANOVA (limited to two levels in two of the factors, and any number of levels in the third). ![]() Tukey, Newman-Keuls, Dunnett, Bonferroni, Holm-Sidak, or Fisher’s LSD multiple comparisons testing main and simple effects. Two-way ANOVA, with repeated measures in one or both factors.Two-way ANOVA, even with missing values with some post tests.Calculate the relative risk and odds ratio with confidence intervals. Fisher's exact test or the chi-square test.Kruskal-Wallis or Friedman nonparametric one-way ANOVA with Dunn's post test.When this is chosen, multiple comparison tests also do not assume sphericity. Greenhouse-Geisser correction so repeated measures one-, two-, and three-way ANOVA do not have to assume sphericity.Many multiple comparisons test are accompanied by confidence intervals and multiplicity adjusted P values.One-way ANOVA without assuming populations with equal standard deviations using Brown-Forsythe and Welch ANOVA, followed by appropriate comparisons tests (Games-Howell, Tamhane T2, Dunnett T3).Ordinary or repeated measures ANOVA followed by the Tukey, Newman-Keuls, Dunnett, Bonferroni or Holm-Sidak multiple comparison tests, the post-test for trend, or Fisher’s Least Significant tests.Perform many t tests at once, using False Discovery Rate (or Bonferroni multiple comparisons) to choose which comparisons are discoveries to study further.Wilcoxon test with confidence interval of median.Kolmogorov-Smirnov test to compare two groups.Nonparametric Mann-Whitney test, including confidence interval of difference of medians.Automatically generate volcano plot (difference vs.Reports P values and confidence intervals. ![]()
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![]() ![]() (2007, December 1). Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin: an American Academy of Sleep Medicine report. Highlights of prescribing information.(2014, June 10). Cataplexy-clinical aspects, pathophysiology and management strategy. Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patients. Cvetkovic-Lopes, V., Bayer, L., Dorsaz, S., Maret, S., Pradervand, S., Dauvilliers, Y., & Tafti, M.Current and future therapeutic approaches in narcolepsy. Cochen De Cock, V., & and Dauvilliers, Y.You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. To help avoid injury from occurring with cataplexy: In regards to safety, even if an individual senses the onset of an episode, injury is very possible with cataplexy. In addition, abrupt withdrawal of venlafaxine can potentially cause rebound cataplexy. However, evidence supporting the use of antidepressants for cataplexy is varied. These include venlafaxine, a serotonin-noradrenaline reuptake inhibitor (SNRI) antidepressant, and tricyclic antidepressants such as clomipramine, imipramine, and desipramine. Other medications that may help control symptoms are antidepressants. This medication should not be used in conjunction with alcohol or any other central nervous system (CNS) depressant due to the risk of respiratory depression and other significant CNS depressant effects. Possible adverse effects are dizziness, headache, and nausea. Sodium oxybate is effective in reducing both the frequency and intensity of attacks. Food and Drug Administration (FDA) for the treatment of cataplexy. Sodium oxybate at doses between 6 and 9 grams (g) nightly is the medication approved by the U.S. scheduling one or more short naps during the day. ![]() ![]() avoiding caffeine in the late afternoon or evening.avoiding a large meal before bedtime and opting for a light, healthful snack if necessary.exercising regularly and maintaining a healthful diet.limiting exposure to light in the evenings.making the bedroom quiet and relaxing and keeping it at a comfortable, cool temperature.striving for at least 7 to 8 hours of sleep, or the amount that normally makes you feel refreshed.keeping a consistent sleep schedule, including getting up and going to bed at the same time every day, even on weekends or during vacations.There is no cure for cataplexy, and treatment is symptom management with good sleep hygiene practices and the use of medication as necessary.Īdditionally, safety measures should be put in place to avoid serious injury that can result from falls. On average, a person with cataplexy will experience one or more episodes each week. The frequency of cataplectic episodes varies from less than one per year to several per day. This autoimmune response causes trib 2 antibodies to form, which target and kill the neurons in the brain that produce hypocretin. ![]() It is thought that narcolepsy may be an autoimmune disorder, but more research is needed.Ī study published in the Journal of Clinical Investigation in 2010 revealed that the loss of hypocretin is caused by an autoimmune response targeting tribbles homolog 2 (trib 2) autoantigens. People with cataplexy have been found to have a certain human leukocyte antigen, variations in T-cell receptors, or dysfunctional immune system responses to certain antigen exposures. Hypocretin is a neurotransmitter involved in the promotion of wakefulness within the sleep/wake cycle, The exact underlying cause of this intrusion is unknown, but a loss of neurons that produce hypocretin (also known as orexin) is thought to be a major contributing factor. The REM sleep disassociation hypothesis suggests that cataplexy is the muscle paralysis that normally occurs during REM sleep intruding into waking hours. ![]() ![]() ![]() Baldur's Gate / Baldur's Gate: Enhanced Edition / Baldur's Gate II: Shadows of Amn / Baldur's Gate II: Enhanced Edition / Baldur's Gate: Enhanced Edition Trilogy (mod) (Enemy Randomizer).Azure Dreams (Game Boy Color) (pro_grammar's).Axiom Verge (Pozzum's) - Version 0.6.2.1 also contained an unbalanced monster randomizer - OBSOLETE.Gensôkyô no Nazo (fangame) (Ryason55's).An Untitled Story (Mokesmoe's) - Support available on the ESA Randomizer Discord server.Super Adventure Island II (abyssonym's).Adventure - See at end of list: Multi-series, Connected worlds.Yakuza: Like a Dragon (Enemy Randomizer)įor older changes, you may consult the full changelog.NEO: The World Ends with You (SaltContainer's).Mega Man Battle Network (Legacy Collection) (Undernet-Trader). ![]()
![]() Fish and Wildlife Service, but ended up destroying the nest. You can also follow George on Twitter and Instagram. Listen live at: 25 and: 55 past the hour. They were careful to follow the advice of the U.S. Starting July 26, get live updates on the Commanders’ training camp from WTOP’s George Wallace. Saturday, participants in the convoy delayed plans to head to the. It started in the Los Angeles area and made its way to Western Maryland on Friday. government offices call their home: The Congress and. The convoy is about 30 to 35 minutes long. Accumulation for much of the area is expected to be between 1 and 4 inches. Heres where beside the President of the United States the two other branches of the U.S. Capitol, focal point of the city and seat of USAs government. They didn’t like the camera, and were attacking it, so highway officials removed the nest. Watch the Capitol and Washington D.C.s Union Station via webcam. Viewers had a front-row seat to life as an osprey. In 2014, a pair of the federally-protected birds built a nest right in front of one of the Maryland Transportation Administration’s traffic cameras. Their incredible hemispheric migration back to their nest at the Bay Bridge dwarfs any vacation getaway, and it’s a shame the construction coincides with their predictable return for breeding season.” “It’s not the most ideal location, above a major highway that carries about 100,000 vehicles every day, but they’re determined. DOT has developed this WWW interface to the Countys ATMS VIDEO MONITORING SYSTEM that allows you to view our traffic monitoring. latest updates on road and transit conditions from WTOPs Traffic Center, area transit officials and more. “They’ve been trying to cobble together a makeshift nest on the gantry all day long Thursday,” said Dave Dildine in the WTOP traffic center. Undeterred by the loss of their platform, a pair of ospreys has returned to the Chesapeake Bay Bridge. ![]() Viewers had a front-row seat to life as an. Business & Finance Click to expand menu. In 2014, a pair of the federally-protected birds built a nest right in front of one of the Maryland Transportation Administration’s traffic cameras. ![]() ![]() ![]() Mission Valley Kid's Book and Craft Club meets the second Monday of each month at 3:30 p.m. ![]() at the Mission Valley Branch Library, 2123 Fenton Parkway, San Diego, CA 92108, 85. Mission Valley Page Turners Book Club meets the first Wednesday of each month at 10:00 a.m. Mission Valley Book Club meets the third Tuesday of each month at 6:30 p.m. at the Mission Hills-Hillcrest Branch Library, 215 W. Mission Hills-Hillcrest Mystery Book Group meets the fourth Wednesday of each month from 3:00 to 4:00 p.m. Mission Hills-Hillcrest Gay Men’s Book Club meets the first Monday of each month at 6:00 p.m. (discussion) at the Mira Mesa Branch Library, 8405 New Salem St., San Diego, CA 92126, 85. Mira Mesa Branch Library Banned Book Discussion Group meets the last Tuesday of each month at 6:30 p.m. at the Kensington-Normal Heights Branch Library, 4121 Adams Ave., San Diego, CA 92116, 61. Kensington Book Discussion Group meets the fourth Monday of each month at 6 p.m. at the College-Rolando Branch Library, 6600 Montezuma Road, San Diego, CA 92115-2828, 61. in the Travel Center area on the 5th floor of the Central Library, 330 Park Blvd., San Diego, CA 92101, (619) 236-5800.Ĭollege-Rolando Branch Library hosts an adult book discussion group on the second Saturday of each month at 10 a.m. at the Carmel Valley Branch Library, 3919 Townsgate Drive, San Diego, CA 92130, 85.Ĭentral Library - Fantastical Fiction Forum, focusing on speculative fiction (fantasy, science fiction, and horror) meets the last Tuesday of each month from 6:30 p.m. The book club does not currently meet in the months of June, July, and August.Ĭarmel Valley Men's and Women's Book Group, meets the first Tuesday of every month from 6:30 p.m. In the month of November and December, the book club will meet on the third Monday. at the Carmel Valley Branch Library, 3919 Townsgate Drive, San Diego, CA 92130, 85. at the Carmel Valley Branch Library, 3919 Townsgate Drive, San Diego, CA 92130, 85.Ĭarmel Valley Teen Book Club, for students in grades 7-12, meets the fourth Monday of the month at 5:00 p.m. * may change to second Tuesdays around holidays.Ĭarmel Valley Child-Parent Book Club, for students in grades 4 to 6 and their parents, meets the first Monday of the month at 5:00 p.m. at the Carmel Mountain Ranch Library, 12095 World Trade Drive, San Diego, CA, 92128. at the Allied Gardens/Benjamin Branch Library, 5188 Zion Ave., San Diego, CA 92120, 61.Ĭarmel Mountain Ranch Library hosts an adult book discussion group on the fourth* Thursday of the month from 10:00 a.m. ![]() at the Allied Gardens/Benjamin Branch Library, 5188 Zion Ave., San Diego, CA 92120, 61.īenjamin Short Classics Book Club meets the fourth Tuesday of each month from 6:30 p.m. to 11:00 a.m., at the Balboa Branch Library, 4255 Mount Abernathy Ave., San Diego, CA 92117, 85.īenjamin Book Club meets the third Tuesday of each month from 1 to 2 p.m. Balboa Book Discussion Group meets the third Tuesday of each month from 10:00 a.m. ![]() ![]() ![]() “Deep Hollow” is an ode to that personal and collective emptiness, to that private limbo, war-torn and battle fatigued, exhausted yet stoic and full of tender beauty.”ĭirected, shot, and edited by Matthew Hoffman on Super 8mm film. ![]() We are like ghosts stumbling in a black and white film of our former lives, trying to re-trace the comfort of our old familiar haunts, seeking shelter and finding only set pieces. Somehow I feel like we all just survived a collective plane crash and are trying our best to “forget it” and “get back to normal”, yet deep down something doesn’t feel right. Somehow this concept of home currently feels totally alien and unattainable. We shot in the Florida swamps near my adolescent home, as well as some of my former haunts in New York City, places I used to call home, all of which feel like strangers to me now. For locations, we chose familiar yet unplaceable post-apocalyptic landscapes that echo this feeling of loss, amnesia, loneliness, and fossilized violence. The rest of the film follows this character– a fictional hybrid between my fantasy of the teenage pilot and my own inner teenager– through a stumbling post-traumatic haze, awkwardly trying to navigate her way back into society. We returned to the scene and re-staged the crash with super 8mm film and smoke bombs. Something about this plane gave me a nauseous feeling.ĭeep down, I kind of felt like that teenage girl, dropped from the sky like Lucifer with no wings and no guidebook on how to navigate this ever-crumbling Paradise Lost. She was less than a mile from the airport. My heart was suspended in my chest.Īfter a bit of sleuthing, we found this local news story about a student pilot that crashed the plane a couple months earlier– a teenage girl– 17 years old– who like me, loved skydiving and extreme sports. We stopped and approached it slowly, not sure if we were about to come across a dead body or a trapped person in need of help. From the looks of it, it appeared as though it had just dropped out of the sky. ![]() “One day Matthew and I were going on a leisurely drive in the countryside and suddenly spotted this downed plane in the middle of a field. I wasn’t sure if it had just crashed, or if it had been there for some time. Today Taraka (ex-Prince Rama) shares a new song and video for “Deep Hollow.” The back story here takes a minute to explain, so here’s Taraka’s own story on how the video came to be: ![]() ![]() ![]() Russian chat rooms now buzz with discussions about its fallibility, and Web sites offer methods to test whether a coded alcoholic has been administered a placebo or a real drug that can cause violent illness when mixed with alcohol. But some doctors fear that the increasing sophistication of the population and the use of the technique against other addictions, such as gambling, are draining the method of its essential ingredient: the power of suggestion. In the last 20 years, hundreds of thousands of people in Russia and other countries of the former Soviet Union have been coded against the desire to drink. "I believed him, because we had all heard stories about people who were coded and died when they drank," said Svetlana, who didn't want her last name published because she said her co-workers didn't know she was an alcoholic. "And if you drink in that time, you will die." He insisted that she sign a release form saying he would bear no responsibility for her death should she drink within 12 months. "I've coded you for a year," he said, according to Svetlana. The injected medicine, the doctor said, would stay in her system. She became dizzy and had difficulty breathing before the doctor stepped in with some oxygen to revive her. Before the drug kicked in, the doctor gave her a little vodka to taste. ![]() In Svetlana's case, that was induced by mild hypnosis followed by injection of a temporary but powerful drug that could attack her respiratory system. Dating to the former Soviet Union, it involves the manipulation of the alcoholic's psyche to create the belief that alcohol equals death. Three months earlier, Svetlana had been "coded" - a catchall term for a Russian method of treating alcoholism that essentially involves scaring the living daylights out of the alcoholic. "I was absolutely sure something terrible would happen to me," she recalled. ![]() ![]() This reading plan will take you through all 260 chapters of the New Testament, one chapter per day. Read through the New Testament in 5 days a week, 5 minutes a day.ĥ minutes a day | If you’re not used to reading the Bible daily, start with this easy to use tool to read a chapter of the New Testament in 5 minutes a day. The 5x5x5 New Testament Bible Reading Plan Be expectant, and let your continual exposure to God’s Word reshape your attitudes and behavior as you gain a better understanding of every part of His written testimony to us. In the year ahead, ask God each day to speak directly to you from the Scripture portions you read. For example, you could read the first reading this year and the second reading next year. If reading through the entire Bible in one year looms as too large a task, you can alter the plan to meet your needs.You’ll have a few extra days each month to meditate more deeply on something that was significant to you in the past week, to catch up on missed readings, or to revisit favorite passages. Each month consists of twenty-five readings.You can begin at any point of the year.The second reading takes you through a chapter of the wisdom literature and Isaiah. The first reading alternates between Old and New Testament books with the Gospels spread throughout the year.The Navigators Book-at-a-Time Bible Reading Plan takes you through the entire Bible in one year, providing two readings for each day. Or Access a Screen Reader Version of This Resource Here Through His Word He will illuminate the path in every area of your life. “Your word is a lamp to my feet and a light to my path” (Psalm 119:105, ESV). Does reading the entire Bible this year feel like too much? This plan promotes creating sacred space for you and the Lord to spend time together. No more dragging your feet through a section of the Bible you find difficult to understand before you can move forward. Adds variety in your daily readings as you daily journey through the Old and New Testament, offering four scripture passages daily.Or you can return to passages where you want to spend more time. You’ll have 25 readings each month, which provides the space to catch up, if needed. Offers three to six free days per month.You don’t have to wait for January 1 to start this plan you can start whenever you like. Provides flexibility with our new and refreshed format, you can begin whenever you like.Here are five reasons our Navigators Bible Reading Plan might be your next step to deepen your time in God’s Word: The Navigators Bible Reading Plan (also known as Discipleship Journal Bible Reading Plan) offers special features that will aid you in your journey through the Bible. Here are three Bible reading plans to choose from, so you may select one that best fits your needs. “The words that I have spoken to you are spirit and life” (John 6:63b, ESV). Time in His Word is always beneficial because it’s transforming us to be more like Jesus. God can’t wait for you to join Him in Scripture and discover how relevant it is to what you’re going through today. ![]() ![]() Choose a DVD menu template from 100+ free designs on the right panel. Step 4 Customize DVD Menu Templates (Optional)Ĭlick on the Menu tab to make customization on DVD menu template with Wondershare DVD Creator. You can skip this step if you want to keep your original videos. ![]() Click the pencil-like icon on the thumbnail to open the Video Editor window, where you can crop, trim, and rotate your videos, or apply effects, add watermarks and subtitles, etc. Step 3 Edit Videos with DVD Creator Freeware Alternative (Optional)Īll added files will be shown as thumbnails on the left panel. Hit this icon to open the search window and choose files present on your computer, or you can directly drag and drop files to the program. Step 2 Import Files to DVD Creator Freeware AlternativeĬlick the " + " button which reminds you to add videos. Then choose Create a DVD Video Disc option on the homepage. Steps on How to Create DVD with Wondershare DVD Creator Freeware Alternative Step 1 Launch DVD Creator Freeware AlternativeĪt the very beginning, you should download, install and launch the DVD creator freeware alternative on your PC/Mac first. In this article, the best 10 DVD creator freeware will be listed so that you can create DVD free.įree Download Free Download Watch Video Tutorial of DVD Creator Freeware Alternative If you want to achieve good results, then you need to get a software that will convert files and write them to your DVD, so that you know that information, be it a movie or documents or photos, is stored and accessible. However, it's not just as simple as buying a blank DVD and sticking it in your PC's CD drive. ![]() Sure, you can use the cloud – but is that really in your control? A DVD is easy to back up to once you know how, it takes up little-to-no space, and it's as good a back-up medium as you can get, provided you store and use it responsibly. That's the only way to ensure that you'll have a backup in case things go wrong. What happens when you want to watch a movie in a different room without a PC? What happens when you want to make a back-up of sensitive documents in the event of a computer malfunction? Yet, what happens when you want to share a copy of family photos with your extended family? You can't just give them your computer. Finally, click the Burn button to start burning videos to DVD.Top 10 Best DVD Creator Freeware to Create DVD Freeįrom your new family videos on your camera, to your bank statements, to the movies you download straight to your PC, we rarely need a tangible copy of anything anymore. Choose Burn to disc option and finish Burn Settings as the window shows. Move to Burn tab and insert a blank disc into your PC. If anything you're not satisfied, just back to the previous options to make adjustments. ![]() For further customization, hit the icons as below to change background music and picture, add text, create chapters, etc.Īfter all changes have been done, go to the Preview tab to check your creation. There are 100+ free templates with different styles on the right interface, double-click to apply your favorite one. Step 3 Edit Video and Choose Template for DVD (Optional)Ĭlick the pencil-like icon on the thumbnail to open the Video Editor window, from where you can crop, trim, rotate videos, or add watermarks, effects, subtitles on your video as you like.Īfter completing video editing, move to the Menu tab and select a menu template design for your DVD. All added files will appear on the left column as thumbnails. You can also simply drag and drop desired videos to the program. Install and launch Wondershare DVD making software on your computer, choose Create a DVD Video Disc option from the interface.Ĭlick the + icon under the Source tab to search and import videos present on your computer. Steps to convert videos to DVD using Wondershare DVD Creator: Step 1 Open Wondershare DVD Making Software Free Download Free Download Video Tutorial of How to Burn Video to DVD with the Best DVD Making Software ![]() ![]() ![]() ![]() The beads are completely self-contained and never fall out. Push the beads down with a pen or finger to erase and start over. Magnetic Drawing Board, Magnetic Ball Sketch Pad Tablet Drawing Board, Find Details and Price about Magnetic Drawing Board, Educational Toys from Magnetic. HOW TO USE - Practice writing on magnetic board, A magnetic stylus pen attract the beads to the surface with an audible click revealing your creation.Small, Light weight in size, easy and convenient to carry. It would be a great joy when pushing down the magnetic balls. EASY TO USE – Toddlers can write with stylus and erase with their little fingers or pens. GIVE YOUR KIDS A BREAK FROM THE SCREEN WITH THIS MAGNETIC PAD.Magnetic STEM toys can help to promote toddlers creativity and imagination, A perfect gift for kids boys girls 3 4 5 6 7 8 9 10 11 12 years old. EARLY EDUCATIONAL LEARNING KIT - Super safe abs plastic strong, durable, BPA free construction IS easy TO clean & non toxic for kids little magnet beads stay self-contained FOR superior safety.AMAZING STEM EDUCATION TOY – Toddlers & preschool & kindergarten students learn creativity while exercising fine motor skills, hand eye coordination & other core training.Vintage CLOWN SHOOT BASE BALL MAGNETIC DART GAME W/ BOX 1 OWNER TIN LITHO. DRAW FREELY MAGNETIC PAD – This magnetic pad would develop kid’s imaginations and explore their creativity with the magnetic beads, using the magnetic tip of the included stylus. Kids Magnetic Ball Sketch Pad Tablet Drawing Pen Board With Magnetic Stylus.In the event that a product reaches damaged, please email us on within 3 working days along with images of the damaged product and we will help you out. If there is any genuine case for exchanges of a product, please contact us on within 3 days of receiving your order & we will handle these exchanges on a case-by-case basis. This is an unparalleled commitment in an eCommerce driven by returns and exchanges. This also means that all the products you receive are. Please call on +91 9601919109 to cancel the order before dispatch.ĭue to hygiene & safety concerns with regards to baby/kids products, Uttam Toys has a strict no exchanges or refunds policy across the website. Orders once placed cannot be cancelled or changed once it has been dispatched. Express delivery charges if applicable will be as per actuals. While we use reputable couriers and work around the clock to ensure your order reaches in time, Uttam Toys cannot be held responsible for shipping delays due natural disasters, strikes, bank holidays or situations beyond our control.Īll shipping is free. We deliver to most part of India within 3-7 days. You will receive an email and/or text message with tracking details once your order has been dispatched. You can reach us at or +91 9601919109 between Monday-Saturday, 11am-7pm incase of any queries. Uttam Toys ships within India only and uses reputable courier companies. Roys is an independent department store, it has a great range of homewares, electricals, toys, gardening, DIY, fashion and groceries all at great prices. Create digital artwork to share online and export to popular image formats JPEG, PNG, SVG, and PDF. We accept all valid debit cards, credit cards, wallet, UPI and Net banking and COD Payment Method. Sketchpad: Free online drawing application for all ages. ![]() |
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